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Saw the thread for Monkey Shines and made me think of another 90s killer animal movie. Man's Best Friend (1993). Stars Lance Hendrickson and Ally Sheedy. Ally Sheedy plays a reporter who sneaks into an animal research facility for an investigative report and finds a dog named Max. It seems friendly and she escapes with it so she can do more reporting on the animal experimentation. The dog is genetically altered and is a killer. It is also famous for one hilarious scene: Yup the dog chases the cat, climbs a tree after it and eats it whole. Also the movie is on youtube.