Wow, this is a tough one. For Von Trier, I'd put "Dogville", "Dancer", and (my favorite) "Melancholia" over "Antichrist", but this isn't an either/or episode.
After I first saw this movie my thought was that it was one of those that I enjoyed, but I never wanted to watch it again. I did for this podcast, and still feel the same way about it. I don't think repeatability is necessary for admittance to The Canon, but I get such a visceral reaction on this. But not in a deep way. "Melancholia" hits me on such a profoundly personal level, and I just don't get that from "Antichrist". Ugh, I'm not being very eloquent here.
In spite of your compelling arguments in the episode, I'm with Amy and am leaning on "no" for this one. It is a symbolic and meaningful movie that sparks thought and discussion, and that's everything that I love; yet it still does not quite hit the mark for me. I've never said to anyone, "You simply HAVE to see Antichrist." I'm in the "no" camp, but it's not a very strong "no".