My favorite part of any episode this season was 431, Ghost Pets are Liars, when Mike O'Brien comes in as a pet medium Chris Dante. I think this episode was a no-brainer for in my top of 2016.
Also episode 399, Gilbert Gottfried, and then Trump and Bernie was excellent. Gilbert was so damn funny.
My top 10 (in no order)
431 ^^
399 ^
442 Andy Daly and Ming
434 with Victor Tiny and Willy
425 - Andy Samberg and Claudia O'Doherty, Nick Kroll
415, Corddy, Gabrus, Brian Husky ( Childrens hospital crew)
453 Johnny Pemberton, Eden Sher, Londale Theus Jr.
407 Paul F. Tompkins, Dan Ahdoot, Drew Tarver, Mandell Maughan, Ryan Gaul, Tawny Newsome, Tim Baltz
408 Live at SXSW 2016: Ben Schwartz, Jon Gabrus, Nick Kroll, Paul F. Tompkins
438 Cameron Esposito, Rhea Butcher, Paul F. Tompkins