Crank III: Hepatitan C
Chev Chelios awakens to find that while his heart is back in place and pumping away, his liver was damaged in the re-implant surgery. Chev's liver begins detoxifying the healthy cells in his body as if they are diseased. In order to survive the beast within, Chev must drink a lot of alcohol to distract his liver from the rest of his body. (Dwight Yoakum explains all of this clearly.) Until Chev can find a new liver, he must become a heroic lush in Crank III: Hepatitan C. Also, some bad guys are trying to kill him and Amy Smart still wants to fuck him in public.