I think this film would be perfect for the podcast. It creeped me the hell out when it came out, and one of the few Siskel & Ebert episodes that I ever saw listed this as one of the worst movies that they had ever seen for that year. Here's a youtube clip of some lines. I couldn't find the trailer.
www.youtube.com/embed/HLAbTbGQcr8
INNERSPACE (1987)
A hapless store clerk must foil criminals to save the life of the man who, miniaturized in a secret experiment, was accidentally injected into him.
Starring Dennis Quaid, Martin Short, Meg Ryan