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Comedian John Mulaney feels falsely modest about being Conan O’Brien’s friend. John and Conan sit down to talk about growing up in a family trapped in the 1950s, the power of dressing well, fulfilling a lifelong dream of a career in comedy, and the rewarding experience of creative his new Netflix show John Mulaney & The Sack Lunch Bunch. Later, Conan and his team share their formative cinematic experiences.

Dr. Alex Monro is a Botanist and research leader at the Royal Botanic Gardens, Kew in the Americas Team of the Identification and Naming Department. After watching The Jungle Book at a young age he became fascinated with tropical forests and has spent the last 20 years working as a taxonomist, systematist and field botanist. Jonathan joined Dr. Monro in his office at the Royal Botanic Gardens to discuss the Millennium Seed Bank Project, stinging nettles, and all the different ways plants reproduce. Follow Dr. Monro on Twitter @alexmonro and the Royal Botanic Gardens on Instagram, Twitter, and Facebook @kewgardens. To find out more about Dr. Monro and RBG’s work visit tropicalbotany.wordpress.com and www.kew.org

ATSUKO OKATSUKA joins The Boys to play some new games for her game show.

Author Casey McQuiston talks about her hit novel Red, White & Royal Blue, gender fluidity in writing, and worrying about parents reading or seeing your work.

TV writer Marcos Luevanos (Charmed) joins Matt and Dave to chat about the power of magic intuition candles, the push to get Shannon Doherty involved in the reboot of Charmed, and finding serendipitous closure after a breakup. Plus, getting ‘found out’ at fourteen while attending an all-boys Catholic school, hooking up in the bathroom during sixth period, and navigating a relationship with conservative Republican parents.

Lou Gonzalez and Jeff Kreisler join Negin to discuss Tuesday’s Democratic debate, the latest on impeachment proceedings and what’s going on in Iran. They also get into the good and bad effects of complaining.

Comedian Nikki Glaser feels overwhelmed about being Conan O’Brien’s friend. Nikki and Conan sit down to discuss modern perspectives on the vagina, the emotional toll of performing a roast, how discovering stand-up comedy helped Nikki manage an eating disorder, and going down in flames with her worst-ever jokes told at a wedding. Plus, Conan responds to the idea of his name on a rump-cheek as he and his staff Review the Reviewers.

Viral sensation Arthur Fleck aka Joker (Kenny Stevenson) joins Matt Besser to talk about the Gotham comedy scene and to workshop some of his material. Plus, Joker and Matt perform two-man scenes based off questions from listener call-ins.

On a special Throwing Shade, astrologer and medium Jessica Lanyadoo (Ghost of a Podcast) joins Bryan and Erin to discuss discovering her passion for astrology and moving to San Francisco to pursue it, incorporating aspects of classical psychology into her readings, her thoughts on rumpology, and much more. Later, Jessica gets in deep with chart readings for both Bryan and Erin – plus, advice on navigating our individual ‘tunnels of shit’.

The Boys welcome back PAUL F. TOMPKINS and MATT GOURLEY to do a Superego.

Wendy Davis came into the spotlight in 2013 when she took to the Texas Senate floor to perform a 13 hour filibuster to block a bill that would severely impact abortion rights. She received her degree from Harvard and practiced law for several years before becoming Texas’s State Senator from 2009 to 2015. She is also the founder of Deeds Not Words, a non-profit organization that focuses on engaging young women in politics. Her and Jonathan sat down backstage in Austin Texas while on the road for his comedy tour to discuss her epic filibuster, the current state of Texas politics and why she’s passionately running for Texas’s 21st Congressional District in 2020! Follow Wendy Davis on Twitter @wendydavis and on Instagram and Facebook @wendydavistexas. To find out more about Wendy’s work visit www.wendydavisforcongress.com

This week, Bryan dives into a breakdown of the feline horror that is the Cats film adaptation before pulling apart the best and the worst of the Golden Globes – plus, Fleabag star Andrew Scott’s oh-so-not scandalous ‘racy’ Grindr photo. Then, Erin pulls back the curtain on the 22 Convention: Make Women Great Again conference, which describes itself as the “ultimate event for women, by men” and the “mansplaining event of the century”. Yikes!

Attorney Carl Charles sits down with Cameron to discuss his work at Lambda Legal.

Actor/comedian Josh Thomas (Please Like Me, Everything’s Gonna Be Okay) joins Matt and Dave to discuss watching every episode of Seinfeld in the last year, the pros/cons of cloning an aging pet, dating while famous, and not being afraid to self-deprecate. Plus, Josh goes into the autobiographical elements of Please Like Me, his reaction to the gay marriage referendum in Australia, and his new show on Freeform, Everything’s Gonna Be Okay.

Ian Roberts, Mookie Blaiklock, and Lou Wilson join Matt Besser for scenes about a bartender who takes sober New Years resolutions personally, agricultural inventions getting repurposed for sex, and an argument about sissy bars. Plus, a Little League ump’s bad call sparks a chain reaction and anti-marriage jokes go a little too far.

The Boys welcome back JON GABRUS to do a different kind of power hour.

Dr. M. Sanjayan was formerly the lead scientist at The Nature Conservancy before becoming the CEO of Conservation International. Together with CI they have created the Amazon Sustainable Landscapes Project which aims to restore 73 million trees in Brazil by 2023. He’s a recipient of UCSC’s Global Oceans Hero Award, a member of National Geographic Society’s Explorers Council and a Disneynature Ambassador. He can be seen co-hosting and hosting several nature based documentaries on BBC, Discovery and PBS to name a few! He joined Jonathan in the studio to discuss how our lives are interconnected with the earth and why saving nature is actually about saving humanity. Follow Dr. M. Sanjayan and Conservation International on Instagram @ConservationOrg, on Twitter @ConservationOrg and @MSanjayan and on Facebook @Conservation.Intl. To find out more about Sanjayan and Conservation International’s work visit www.conservation.org.

Basketball legend Charles Barkley feels great about being Conan O’Brien’s friend. Charles and Conan sit down to chat about the extreme competition of going pro, getting booed offstage at a Katy Perry concert for dissing the Timberwolves, his friendship with Shaq, and advocating for education. Later, Conan issues a warning to his staff about spoiling certain tv shows.

Actor/musican Jack Black feels shitty about being Conan O’Brien’s friend. Jack and Conan sit down to talk about the 1999 pilot Heat Vision and Jack, laying down hot tracks with Jack White, bringing the energy to max performing with Tenacious D, the greatest mobile golf game, and the later films of Ruth Gordon. Plus, Conan issues another State of the Podcast address.

In this first episode of 2020, Negin talks with Peter Grosz and Justin Krebs about the highs and lows of the last decade. She also dissects a “Secret Concierge Service” with Myq Kaplan, and Jody Avirgan.

Live from the London Podcast Festival, Dave and Matt are joined by rock star Martin Rossiter, comedian Kayleigh Llewellyn, and writer Brian J. Moylan to dish on Real Housewives updates, Ben and Arthur (and other trash classics), favorite childhood films, and relationship origin stories. Plus, Brian tells his saddest R-rated story about trying to get laid in the UK.

Jonathan Braylock and James III of Astronomy Club join Lisa Gilroy and Matt Besser for this week’s improv4humans! They’ll perform scenes about a friend with an Aladdin kick, taking bites from a candy house, and doodling for catfish. Plus, special interviews with Arkansas Razorbacks coach Eric Musselman and famed Florida Gator Man Robby Stratton. Check out Astronomy Club: The Sketch Show streaming now on Netflix.

Welcome to 2020! For the first Throwing Shade of the year, Erin talks about Ohio representative John Becker, who authored the infamous ectopic pregnancy abortion bill without consulting a single doctor about whether the procedure is even possible (it’s not). Then, Bryan discusses a story out of West Plains, Missouri about a group of high school students who unfurled a Confederate flag in response to their classmates handing out rainbow flags.

Author, comedian, and former senator Al Franken is already a f***ing friend of Conan O’Brien’s. Al and Conan sit down to talk about favorite SNL sketches that never made it to air, doing ‘The Brain Tumor Comedian’ with Tom Davis, shutting down George Harrison’s drunken piano playing, and the jokes that failed to land with guests of The Al Franken Podcast. Plus, Conan follows up on the resurfacing of his correspondence with iconic writer E.B. White.

Dr. Celeste Watkins-Hayes received her M.A. and Ph.D in Sociology from Harvard and is a Professor of Sociology and African American Studies and Faculty Fellow at Northwestern University. Her first book titled “The New Welfare Bureaucrats: Entanglements of Race, Class, and Policy Reform” and most recent release “Remaking a Life: How Women Living with HIV/AIDS Confront Inequality” bring to light the uncomfortable fact that racism is still disproportionately affecting people of color in many ways. In the fall of 2019 Jonathan released his book “Over The Top” where he disclosed his HIV positive status which prompted Dr. Watkins-Hayes to write an op-ed on the subject in the NY Times. This inspired the two of them to get together to discuss issues they are both passionate about. Follow Dr. Celeste Watkins-Hayes on Instagram @celestewatkinshayes, on Twitter @watkinshayes and on Facebook @celeste.watkinhayes. To find out more about Celeste’s work visit www.celestewatkinshayes.com